MicroRNA-27a Promotes the Proliferation and Invasiveness of Colon Cancer Cells by Targeting SFRP1 through the Wnt/β-Catenin Signaling Pathway | Zendy

Sang Ba | Zendy; Yi Xuan | Zendy; Ziwen Long | Zendy; Haiyong Chen | Zendy; Shusen Zheng | Zendy

Open Access

MicroRNA-27a Promotes the Proliferation and Invasiveness of Colon Cancer Cells by Targeting SFRP1 through the Wnt/β-Catenin Signaling Pathway

Author(s) -

Sang Ba,

Yi Xuan,

Ziwen Long,

Haiyong Chen,

Shusen Zheng

Publication year - 2017

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000479610

Subject(s) - wnt signaling pathway , cyclin d1 , microrna , transfection , cell growth , cancer research , biology , catenin , colorectal cancer , microbiology and biotechnology , blot , signal transduction , cell culture , cancer , cell , cell cycle , gene , biochemistry , genetics

This study aims to explore the effects of microRNA-27a (miR-27a) on the proliferation and invasiveness of colon cancer cells through the Secreted Frizzled-related protein 1 (SFRP1) and the Wnt/β-catenin signaling pathway.

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