Open AccessBrain Malformations Do Not Predict Hypopituitarism in Young Children with Optic Nerve Hypoplasia
Author(s) -
Pamela GarciaFilion,
Hashem Almarzouki,
Cassandra Fink,
Mitchell E. Geffner,
Marvin D. Nelson,
Mark Borchert
Publication year - 2017
Publication title -
hormone research in paediatrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.816
H-Index - 89
eISSN - 1663-2826
pISSN - 1663-2818
DOI - 10.1159/000479029
Subject(s) - optic nerve hypoplasia , hypopituitarism , medicine , hypoplasia , endocrinology
Optic nerve hypoplasia (ONH), a leading cause of pediatric blindness, is associated with brain malformations and hypopituitarism in the constellation known as septo-optic dysplasia. Neuroimaging is used to anticipate hypopituitarism, but with unconfirmed reliability. We report prospective findings on the association of hypopituitarism with brain malformations.
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