Identification and Characterization of Long Non-Coding RNAs in Osteogenic Differentiation of Human Adipose-Derived Stem Cells | Zendy

Guangxin Huang | Zendy; Yan Kang | Zendy; Zhiyu Huang | Zendy; Zhiqi Zhang | Zendy; Fangang Meng | Zendy; Weishen Chen | Zendy; Ming Fu | Zendy; WeiMing Liao | Zendy; Ziji Zhang | Zendy

Open Access

Identification and Characterization of Long Non-Coding RNAs in Osteogenic Differentiation of Human Adipose-Derived Stem Cells

Author(s) -

Guangxin Huang,

Yan Kang,

Zhiyu Huang,

Zhiqi Zhang,

Fangang Meng,

Weishen Chen,

Ming Fu,

WeiMing Liao,

Ziji Zhang

Publication year - 2017

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000478751

Subject(s) - runx2 , biology , gene knockdown , microbiology and biotechnology , cellular differentiation , long non coding rna , stem cell , gene silencing , microarray analysis techniques , microrna , gene expression , downregulation and upregulation , gene , genetics

Long noncoding RNAs (lncRNAs) play important roles in stem cell differentiation. However, their role in osteogenesis of human adipose-derived stem cells (ASCs), a promising cell source for bone regeneration, remains unknown. Here, we investigated the expression profile and potential roles of lncRNAs in osteogenic differentiation of human ASCs.

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