Knockdown of ARK5 Expression Suppresses Invasion and Metastasis of Gastric Cancer
Author(s) -
Dehu Chen,
Guiyuan Liu,
Ning Xu,
Xiaolan You,
HaiHua Zhou,
Xiaojun Zhao,
Qinghong Liu
Publication year - 2017
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000478685
Subject(s) - gene knockdown , cancer research , metastasis , pi3k/akt/mtor pathway , western blot , slug , immunohistochemistry , cancer , in vivo , biology , epithelial–mesenchymal transition , kinase , medicine , signal transduction , cell culture , microbiology and biotechnology , immunology , gene , biochemistry , genetics
Gastric cancer (GC) is a common and lethal malignancy, and AMP-activated protein kinase-related kinase 5 (ARK5) has been discovered to promote cancer metastasis in certain types of cancer. In this study, we explored the role of ARK5 in GC invasion and metastasis.
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