Neuroprotective Effects of Pycnogenol Against Oxygen-Glucose Deprivation/Reoxygenation-Induced Injury in Primary Rat Astrocytes via NF-κB and ERK1/2 MAPK Pathways | Zendy

Ruixue Xia | Zendy; Chunxue Ji | Zendy; Leguo Zhang | Zendy

Open Access

Neuroprotective Effects of Pycnogenol Against Oxygen-Glucose Deprivation/Reoxygenation-Induced Injury in Primary Rat Astrocytes via NF-κB and ERK1/2 MAPK Pathways

Author(s) -

Ruixue Xia,

Chunxue Ji,

Leguo Zhang

Publication year - 2017

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000478681

Subject(s) - neuroprotection , mapk/erk pathway , reactive oxygen species , astrocyte , pharmacology , chemistry , oxidative stress , medicine , signal transduction , neuroscience , biology , endocrinology , central nervous system , biochemistry

Pycnogenol (PYC) is a patented mix of bioflavonoids with potent anti-oxidant and anti-inflammatory properties. In this study, we investigated the effects of PYC on oxygen-glucose deprivation/reoxygenation (OGD/R)-induced injury in primary rat astrocytes.

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