Regulation of AP-1 by MAPK Signaling in Metal-Stressed Sea Anemone | Zendy

Maayan Agron | Zendy; Vera Brekhman | Zendy; David Morgenstern | Zendy; Tamar Lotan | Zendy

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Regulation of AP-1 by MAPK Signaling in Metal-Stressed Sea Anemone

Author(s) -

Maayan Agron,

Vera Brekhman,

David Morgenstern,

Tamar Lotan

Publication year - 2017

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000478678

Subject(s) - bilateria , biology , microbiology and biotechnology , transcription factor , mapk/erk pathway , sea anemone , phosphorylation , signal transduction , p38 mitogen activated protein kinases , kinase , gene , genetics , botany , phylogenetics

AP-1 transcription factor plays a conserved role in the immediate response to stress. Activation of AP-1 members jun and fos is mediated by complex signaling cascades to control cell proliferation and survival. To understand the evolution of this broadly-shared pathway, we studied AP-1 regulation by MAPK signaling in a basal metazoan.

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