Open AccessMicroRNA-133b Ameliorates Allergic Inflammation and Symptom in Murine Model of Allergic Rhinitis by Targeting Nlrp3
Author(s) -
Lifeng Xiao,
Jiang Li,
Qi Hu,
Yuru Li
Publication year - 2017
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000478645
Subject(s) - proinflammatory cytokine , mucous membrane of nose , ovalbumin , immunoglobulin e , immunology , tumor necrosis factor alpha , eosinophil , inflammation , medicine , immune system , antibody , asthma
Emerging evidences indicate that post-transcriptional regulation by microRNAs is critical in allergic rhinitis (AR) pathogenesis. MircroRNA-133b (miR-133b) was recently suggested as a potential predictor of AR. However, the in vivo effect of miR-133b on AR is unclear.
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