Impact of Body Site, Age, and Gender on the Collagen/Elastin Index by Noninvasive in vivo Vertical Two-Photon Microscopy | Zendy

Carolin Czekalla | Zendy; KarlHeinz Schönborn | Zendy; Nadine Döge | Zendy; Sora Jung | Zendy; Maxim E. Darvin | Zendy; Jürgen Lademann | Zendy; Martina C. Meinke | Zendy

Open Access

Impact of Body Site, Age, and Gender on the Collagen/Elastin Index by Noninvasive in vivo Vertical Two-Photon Microscopy

Author(s) -

Carolin Czekalla,

KarlHeinz Schönborn,

Nadine Döge,

Sora Jung,

Maxim E. Darvin,

Jürgen Lademann,

Martina C. Meinke

Publication year - 2017

Publication title -

skin pharmacology and physiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.703

H-Index - 74

eISSN - 1660-5535

pISSN - 1660-5527

DOI - 10.1159/000477854

Subject(s) - elastin , dermis , extracellular matrix , skin aging , in vivo , anatomy , autofluorescence , pathology , chemistry , elastic fiber , medicine , biomedical engineering , biology , dermatology , optics , biochemistry , physics , microbiology and biotechnology , fluorescence

Extrinsic and intrinsic skin aging is subject to constant remodeling and degradation processes, primarily in components of the extracellular matrix. While collagen fibers thin out during the aging process, the amorphous elastin fibers accumulate. These are essential formative components of the dermis. So far, these processes have been detected in vertical histological sections of invasive biopsies and recently in noninvasive horizontal scans.

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