Protective Effects of MicroRNA-126 on Human Cardiac Microvascular Endothelial Cells Against Hypoxia/Reoxygenation-Induced Injury and Inflammatory Response by Activating PI3K/Akt/eNOS Signaling Pathway | Zendy

Honghui Yang | Zendy; Yan Chen | Zendy; Chuanyu Gao | Zendy; Zhen-Tian Cui | Zendy; Jian-min Yao | Zendy

Open Access

Protective Effects of MicroRNA-126 on Human Cardiac Microvascular Endothelial Cells Against Hypoxia/Reoxygenation-Induced Injury and Inflammatory Response by Activating PI3K/Akt/eNOS Signaling Pathway

Author(s) -

Honghui Yang,

Yan Chen,

Chuanyu Gao,

Zhen-Tian Cui,

Jian-min Yao

Publication year - 2017

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000477597

Subject(s) - wortmannin , enos , pi3k/akt/mtor pathway , protein kinase b , apoptosis , signal transduction , biology , proinflammatory cytokine , nitric oxide synthase , chemistry , nitric oxide , microbiology and biotechnology , inflammation , immunology , endocrinology , biochemistry

This study explored the protective effects of the microRNA-126 (miR-126)-mediated PI3K/Akt/eNOS signaling pathway on human cardiac microvascular endothelial cells (HCMECs) against hypoxia/reoxygenation (H/R)-induced injury and the inflammatory response.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research