Antimelanogenic Efficacy of Melasolv (3,4,5-Trimethoxycinnamate Thymol Ester) in Melanocytes and Three-Dimensional Human Skin Equivalent | Zendy

John Hwan Lee | Zendy; Eun-Soo Lee | Zendy; IlHong Bae | Zendy; Jeong-Ah Hwang | Zendy; Se-Hwa Kim | Zendy; Dae-Yong Kim | Zendy; Nok-Hyun Park | Zendy; Ho Sik Rho | Zendy; Yong Jin Kim | Zendy; SeongGeun Oh | Zendy; Chang Seok Lee | Zendy

Open Access

Antimelanogenic Efficacy of Melasolv (3,4,5-Trimethoxycinnamate Thymol Ester) in Melanocytes and Three-Dimensional Human Skin Equivalent

Author(s) -

John Hwan Lee,

Eun-Soo Lee,

IlHong Bae,

Jeong-Ah Hwang,

Se-Hwa Kim,

Dae-Yong Kim,

Nok-Hyun Park,

Ho Sik Rho,

Yong Jin Kim,

SeongGeun Oh,

Chang Seok Lee

Publication year - 2017

Publication title -

skin pharmacology and physiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.703

H-Index - 74

eISSN - 1660-5535

pISSN - 1660-5527

DOI - 10.1159/000477356

Subject(s) - thymol , human skin , dermatology , chemistry , psychology , biology , food science , medicine , essential oil , genetics

Excessive melanogenesis often causes unaesthetic hyperpigmentation. In a previous report, our group introduced a newly synthesized depigmentary agent, Melasolv™ (3,4,5-trimethoxycinnamate thymol ester). In this study, we demonstrated the significant whitening efficacy of Melasolv using various melanocytes and human skin equivalents as in vitro experimental systems.

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