Role of Immune Cells in Acute Kidney Injury and Repair | Zendy

Sul A Lee | Zendy; Sanjeev Noel | Zendy; Mohanraj Sadasivam | Zendy; Abdel R.A. Hamad | Zendy; Hamid Rabb | Zendy

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Role of Immune Cells in Acute Kidney Injury and Repair

Author(s) -

Sul A Lee,

Sanjeev Noel,

Mohanraj Sadasivam,

Abdel R.A. Hamad,

Hamid Rabb

Publication year - 2017

Publication title -

the nephron journals/nephron journals

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.951

H-Index - 72

eISSN - 2235-3186

pISSN - 1660-8151

DOI - 10.1159/000477181

Subject(s) - medicine , acute kidney injury , kidney disease , immune system , pathophysiology , immunopathology , disease , kidney , intensive care medicine , nephrology , immunology , pathology

Acute kidney injury (AKI) is a significant problem in both native and transplant kidneys. There have been significant advances in understanding the role of immune cells in the early injury and repair from AKI. In this brief review, we aim to update information on the pathophysiologic impact of various immune cells in AKI, with special emphasis on repair. An improved understanding of the AKI immunopathology will lead to new therapies that prevent AKI, accelerate repair, and prevent the progression of AKI to chronic kidney disease.

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