Long Non-Coding RNA XLOC_008466 Functions as an Oncogene in Human Non-Small Cell Lung Cancer by Targeting miR-874 | Zendy

Rui Yang | Zendy; Ping Li | Zendy; Guojun Zhang | Zendy; Chunya Lu | Zendy; Huaqi Wang | Zendy; Guoqiang Zhao | Zendy

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Long Non-Coding RNA XLOC_008466 Functions as an Oncogene in Human Non-Small Cell Lung Cancer by Targeting miR-874

Author(s) -

Rui Yang,

Ping Li,

Guojun Zhang,

Chunya Lu,

Huaqi Wang,

Guoqiang Zhao

Publication year - 2017

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000477121

Subject(s) - cancer research , biology , oncogene , a549 cell , microrna , apoptosis , cell cycle , gene , biochemistry

The therapy and prognosis of lung cancer are difficult because of multiple genetic and epigenetic alterations. Long non-coding RNAs (lncRNAs) have been verified as new mediators of cancer development and progression by virtue of their various functions. Here, we focused on the lncRNA XLOC_008466 based on previous microarray data. However, whether aberrant expression of XLOC_008466 in human non-small cell lung cancer (NSCLC) is correlated with malignancy, metastasis or prognosis has not been elucidated.

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