Salidroside Attenuates Ventilation Induced Lung Injury via SIRT1-Dependent Inhibition of NLRP3 Inflammasome
Author(s) -
Yan Wang,
ChuFan Xu,
Yujian Liu,
Yanfei Mao,
Lv Zhou,
Siyuan Li,
Xiaoyan Zhu,
Lai Jiang
Publication year - 2017
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000477112
Subject(s) - salidroside , inflammasome , pharmacology , ventilation (architecture) , lung , chemistry , rhodiola rosea , evans blue , in vivo , medicine , secretion , immunology , biochemistry , endocrinology , biology , inflammation , mechanical engineering , microbiology and biotechnology , engineering
Salidroside (SDS) is the main effective ingredient of Rhodiola rosea L with a variety of pharmacologic properties. We aim to investigate the effects of SDS on ventilation induced lung injury (VILI) and explore the possible underlying molecular mechanism.
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