The Sodium-Glucose Co-Transporter 2 Inhibitor, Empagliflozin, Protects against Diabetic Cardiomyopathy by Inhibition of the Endoplasmic Reticulum Stress Pathway
Author(s) -
Yang Zhou,
Wei Wu
Publication year - 2017
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000475942
Subject(s) - empagliflozin , diabetic cardiomyopathy , endocrinology , medicine , empa , western blot , chop , endoplasmic reticulum , cardiomyopathy , pharmacology , diabetes mellitus , chemistry , heart failure , type 2 diabetes , biochemistry , mineralogy , lymphoma , electron microprobe , gene
This study aimed to determine whether or not the sodium-glucose co-transporter 2 inhibitor, empagliflozin (EMPA), can protect against diabetic cardiomyopathy (DCM) and to elucidate the related mechanism.
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