MicroRNA-1185 Induces Endothelial Cell Apoptosis by Targeting UVRAG and KRIT1 | Zendy

Haoyuan Deng | Zendy; Xia Chu | Zendy; Zhenfeng Song | Zendy; Xinrui Deng | Zendy; Huan Xu | Zendy; Yaxin Ye | Zendy; Songtao Li | Zendy; Qiao Zhang | Zendy; Changhao Sun | Zendy; Ying Li | Zendy

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MicroRNA-1185 Induces Endothelial Cell Apoptosis by Targeting UVRAG and KRIT1

Author(s) -

Haoyuan Deng,

Xia Chu,

Zhenfeng Song,

Xinrui Deng,

Huan Xu,

Yaxin Ye,

Songtao Li,

Qiao Zhang,

Changhao Sun,

Ying Li

Publication year - 2017

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000475571

Subject(s) - apoptosis , microrna , transfection , microbiology and biotechnology , endothelial stem cell , pathogenesis , small interfering rna , cancer research , endothelium , cell , biology , immunology , cell culture , gene , in vitro , genetics

Atherosclerosis is a multifactorial chronic disease and is the main cause of death and impairment in the world. Endothelial injury and apoptosis play a crucial role in the onset and development of atherosclerosis. MicroRNAs (miRNAs) have been proven to be involved in the pathogenesis of atherosclerosis. However, studies of the functional role of apoptosis-related miRNAs in the endothelium during atherogenesis are limited.

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