Defective Platelet Activation and Bleeding Complications upon Cholestasis in Mice | Zendy

Nina Sarah Gowert | Zendy; Meike Klier | Zendy; Maria Reich | Zendy; Friedrich Reusswig | Zendy; L Donner | Zendy; Verena Keitel | Zendy; Dieter Häussinger | Zendy; Margitta Elvers | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Defective Platelet Activation and Bleeding Complications upon Cholestasis in Mice

Author(s) -

Nina Sarah Gowert,

Meike Klier,

Maria Reich,

Friedrich Reusswig,

L Donner,

Verena Keitel,

Dieter Häussinger,

Margitta Elvers

Publication year - 2017

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000475566

Subject(s) - platelet , platelet activation , gpvi , hemostasis , endocrinology , medicine , thrombus , platelet glycoprotein gpiib iiia complex , platelet membrane glycoprotein , chemistry , platelet adhesiveness , bleeding time , platelet aggregation

Platelets are essential mediators of hemostasis to avoid excessive blood loss. Cirrhosis and chronic liver diseases are characterized by alterations in hemostasis. Alterations in the secondary hemostasis have been well studied, while defects in primary hemostasis, especially the consequences of cholestatic liver disease on platelet function are not well defined.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research