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Identification of Two Additional Susceptibility Loci for Inflammatory Bowel Disease in a Chinese Populationy
Author(s) -
Xiucai Lan,
Xiuhua Lan,
Ying Chang,
Xiaomin Zhang,
Jing Liu,
Vikash Vikash,
Wei Wang,
Meifang Huang,
Xiaobing Wang,
Feng Zhou,
Liping Chen,
Qiu Zhao
Publication year - 2017
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000475439
Subject(s) - inflammatory bowel disease , identification (biology) , disease , biology , genetics , medicine , immunology , computational biology , botany
To investigate the associations between the rs1250569 (zinc finger MIZ-type containing 1, ZMIZ1), rs1042522 (tumour protein p53, TP53), and rs10114470 (tumour necrosis factor-like cytokine 1A, TL1A) polymorphisms and the development of inflammatory bowel disease (IBD) in a Chinese (Han) population. We analysed the expression of genes that predispose patients to Crohn's disease (CD) and ulcerative colitis (UC).

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