Salvianolic Acid A Protects H9c2 Cells from Arsenic Trioxide-Induced Injury via Inhibition of the MAPK Signaling Pathway
Author(s) -
Jingyi Zhang,
Guibo Sun,
Yun Luo,
Min Wang,
Wei Wang,
Yuyang Du,
Yingli Yu,
Xiaobo Sun
Publication year - 2017
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000472409
Subject(s) - viability assay , arsenic trioxide , apoptosis , mapk/erk pathway , microbiology and biotechnology , annexin , chemistry , reactive oxygen species , mtt assay , signal transduction , intracellular , p38 mitogen activated protein kinases , biology , biochemistry
This study aimed to investigate whether Salvianolic acid A (Sal A) conferred cardiac protection against Arsenic trioxide (ATO)-induced cardiotoxicity in H9c2 cells by inhibiting MAPK pathways activation.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom