Osteopontin, Bone Morphogenetic Protein-4, and Vitamin D Receptor Gene Polymorphisms in the Susceptibility and Clinical Severity of Spinal Tuberculosis | Zendy

Guohua Wang | Zendy; Liangyi Xie | Zendy; Jianzhong Hu | Zendy; Hongbin Lü | Zendy; Xiangyang Liu | Zendy; Yong Cao | Zendy; Bin Liu | Zendy; Yi Zhang | Zendy; Xiongjie Shen | Zendy

Open Access

Osteopontin, Bone Morphogenetic Protein-4, and Vitamin D Receptor Gene Polymorphisms in the Susceptibility and Clinical Severity of Spinal Tuberculosis

Author(s) -

Guohua Wang,

Liangyi Xie,

Jianzhong Hu,

Hongbin Lü,

Xiangyang Liu,

Yong Cao,

Bin Liu,

Yi Zhang,

Xiongjie Shen

Publication year - 2017

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000471935

Subject(s) - osteopontin , calcitriol receptor , bone morphogenetic protein , tuberculosis , medicine , receptor , bone morphogenetic protein 6 , gene , bone morphogenetic protein receptor , bone morphogenetic protein 2 , vitamin d and neurology , endocrinology , biology , bone morphogenetic protein 7 , cancer research , pathology , genetics , in vitro

Spinal tuberculosis (TB) is a common and dangerous form of extrapulmonary TB with unclear mechanisms in its occurrence and progression. This study investigated the clinical significances of bone morphogenetic protein-4 (BMP-4), osteopontin (OPN), and vitamin D receptor (VDR) gene polymorphism, mRNA and protein expression in spinal TB patients.

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