Exogenous Hydrogen Sulfide Ameliorates Diabetes-Associated Cognitive Decline by Regulating the Mitochondria-Mediated Apoptotic Pathway and IL-23/IL-17 Expression in db/db Mice | Zendy

Shuainan Ma | Zendy; Di Zhong | Zendy; Pingwei Ma | Zendy; Guozhong Li | Zendy; Wei Hua | Zendy; Yu Sun | Zendy; Ning Liu | Zendy; Linxue Zhang | Zendy; Weihua Zhang | Zendy

Open Access

Exogenous Hydrogen Sulfide Ameliorates Diabetes-Associated Cognitive Decline by Regulating the Mitochondria-Mediated Apoptotic Pathway and IL-23/IL-17 Expression in db/db Mice

Author(s) -

Shuainan Ma,

Di Zhong,

Pingwei Ma,

Guozhong Li,

Wei Hua,

Yu Sun,

Ning Liu,

Linxue Zhang,

Weihua Zhang

Publication year - 2017

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000471932

Subject(s) - tunel assay , apoptosis , sodium hydrosulfide , western blot , endocrinology , medicine , morris water navigation task , chemistry , diabetes mellitus , signal transduction , mitochondrion , microbiology and biotechnology , biology , hippocampus , hydrogen sulfide , biochemistry , sulfur , organic chemistry , gene

Diabetes-associated cognitive decline (DACD) is one of the complications of diabetes and leads to cognitive impairment and an increased risk of dementia. However, the exact mechanism of DACD has not been fully characterized, and a successful therapy for this issue has not been established. This study aimed to detect the anti-apoptotic and anti-inflammatory effects of hydrogen sulfide (H2S) on DACD.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research