Metformin-Associated Lactic Acidosis Undergoing Renal Replacement Therapy in Intensive Care Units: A Five-Million Population-Based Study in the North-West of Italy | Zendy

Filippo Mariano | Zendy; Marco Pozzato | Zendy; Paola Inguaggiato | Zendy; Cesare Guarena | Zendy; E Turello | Zendy; Massimo Manes | Zendy; P David | Zendy; Silvia Berutti | Zendy; Valentina Consiglio | Zendy; Alessandro Amore | Zendy; Andrea Campo | Zendy; Angela Marino | Zendy; Mauro Berto | Zendy; Paola Carpani | Zendy; G Calabrese | Zendy; Maurizio Gherzi | Zendy; E Stramigi | Zendy; Guido Martina | Zendy; Andrea Serra | Zendy; Luciano Comune | Zendy; Elisabetta Roscini | Zendy; Antonio Marciello | Zendy; Vincenzo Todini | Zendy; Patrizia Vio | Zendy; Oliviero Filiberti | Zendy; R Boero | Zendy; Vincenzo Cantaluppi | Zendy

Open Access

Metformin-Associated Lactic Acidosis Undergoing Renal Replacement Therapy in Intensive Care Units: A Five-Million Population-Based Study in the North-West of Italy

Author(s) -

Filippo Mariano,

Marco Pozzato,

Paola Inguaggiato,

Cesare Guarena,

E Turello,

Massimo Manes,

P David,

Silvia Berutti,

Valentina Consiglio,

Alessandro Amore,

Andrea Campo,

Angela Marino,

Mauro Berto,

Paola Carpani,

G Calabrese,

Maurizio Gherzi,

E Stramigi,

Guido Martina,

Andrea Serra,

Luciano Comune,

Elisabetta Roscini,

Antonio Marciello,

Vincenzo Todini,

Patrizia Vio,

Oliviero Filiberti,

R Boero,

Vincenzo Cantaluppi

Publication year - 2017

Publication title -

blood purification

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.686

H-Index - 57

eISSN - 1421-9735

pISSN - 0253-5068

DOI - 10.1159/000471917

Subject(s) - renal replacement therapy , medicine , metformin , dialysis , lactic acidosis , population , acute kidney injury , oliguria , intensive care , intensive care medicine , renal function , insulin , environmental health

Metformin-associated lactic acidosis (MALA) is a severe complication of drug administration with significant morbidity and mortality. So far no study in large population areas have examined the incidence, clinical profile and outcome of acute kidney injury (AKI)-MALA patients admitted in intensive care units (ICUs) and treated by renal replacement therapy (MALA-RRT).

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