Pro-Inflammatory Cytokine TNF-α Attenuates BMP9-Induced Osteo/ Odontoblastic Differentiation of the Stem Cells of Dental Apical Papilla (SCAPs) | Zendy

Feilong Wang | Zendy; Ying Jiang | Zendy; Xia Huang | Zendy; Qiao Liu | Zendy; Yan Zhang | Zendy; Wenping Luo | Zendy; Fugui Zhang | Zendy; Pengfei Zhou | Zendy; Lin Ju-hong | Zendy; Hongmei Zhang | Zendy

Open Access

Pro-Inflammatory Cytokine TNF-α Attenuates BMP9-Induced Osteo/ Odontoblastic Differentiation of the Stem Cells of Dental Apical Papilla (SCAPs)

Author(s) -

Feilong Wang,

Ying Jiang,

Xia Huang,

Qiao Liu,

Yan Zhang,

Wenping Luo,

Fugui Zhang,

Pengfei Zhou,

Lin Ju-hong,

Hongmei Zhang

Publication year - 2017

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000471865

Subject(s) - dental pulp stem cells , periodontitis , cytokine , alkaline phosphatase , proinflammatory cytokine , osteopontin , tumor necrosis factor alpha , stem cell , inflammation , microbiology and biotechnology , medicine , chemistry , immunology , biology , biochemistry , enzyme

Periapical periodontitis is a common oral disease caused by bacterial invasion of the tooth pulp, which usually leads to local release of pro-inflammatory cytokines and osteolytic lesion. This study is intended to examine the effect of TNF-α on BMP9-induced osteogenic differentiation of the stem cells of dental apical papilla (SCAPs).

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