Improved Neural Regeneration with Olfactory Ensheathing Cell Inoculated PLGA Scaffolds in Spinal Cord Injury Adult Rats
Author(s) -
Changxing Wang,
Chenglong Sun,
Zhiying Hu,
Xue Huo,
Yang Yang,
Xuehong Liu,
Benson O. A. Botchway,
Henry Davies,
Marong Fang
Publication year - 2017
Publication title -
neurosignals
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.755
H-Index - 67
eISSN - 1424-8638
pISSN - 1424-862X
DOI - 10.1159/000471828
Subject(s) - olfactory ensheathing glia , luxol fast blue stain , glial fibrillary acidic protein , spinal cord injury , astrocyte , spinal cord , nissl body , remyelination , axon , glial scar , plga , regeneration (biology) , biology , neuroscience , microbiology and biotechnology , pathology , central nervous system , medicine , olfactory bulb , staining , myelin , immunohistochemistry , biochemistry , in vitro
Every year, around the world, between 250000 and 5 people suffer from spinal cord injury (SCI). This study investigated the potential for poly (lactic-co-glycolic acid) (PLGA) complex inoculated with olfactory ensheathing cells (OECs) to treat spinal cord injury in a rat model.
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