Open AccessPlatelets as a Novel Source of Pro-Inflammatory Chemokine CXCL14
Author(s) -
Alexander Witte,
Madhumita Chatterjee,
Florian Läng,
Meinrad Gawaz
Publication year - 2017
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000471821
Subject(s) - cxcl14 , chemokine , monocyte , chemotaxis , platelet , platelet activation , chemistry , flow cytometry , microbiology and biotechnology , biology , receptor , immunology , chemokine receptor , biochemistry
Platelets are a major source of chemokines. Here, we demonstrate for the first time that platelets express significant amounts of CXCL14 and disclose powerful effects of platelet-derived CXCL14 on monocyte and endothelial migration.
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