Baicalein, a Natural Anti-Cancer Compound, Alters MicroRNA Expression Profiles in Bel-7402 Human Hepatocellular Carcinoma Cells
Author(s) -
Beibei Bie,
Jin Sun,
Jun Li,
Ying Guo,
Wei Jiang,
Chen Huang,
Jun Yang,
Zongfang Li
Publication year - 2017
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000470815
Subject(s) - baicalein , cell growth , pi3k/akt/mtor pathway , microrna , cell cycle , protein kinase b , cancer research , wnt signaling pathway , cell culture , biology , microbiology and biotechnology , cell , chemistry , signal transduction , pharmacology , gene , biochemistry , genetics
Baicalein has been shown to possess significant anti-hepatoma activity by inhibiting cell proliferation. Whether the anti-proliferative effect of baicalein is related to its modulation of miRNA expression in hepatocellular carcinoma (HCC) is still unknown.
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