Quantitative Proteomics Analysis of Ischemia/Reperfusion Injury-Modulated Proteins in Cardiac Microvascular Endothelial Cells and the Protective Role of Tongxinluo | Zendy

Qing Li | Zendy; Hehe Cui | Zendy; Yue-jin Yang | Zendy; Xiangdong Li | Zendy; Gui-Hao Chen | Zendy; Xiaqiu Tian | Zendy; Chen Jin | Zendy; QiuTing Dong | Zendy; Peisen Huang | Zendy; Jun Xu | Zendy

Open Access

Quantitative Proteomics Analysis of Ischemia/Reperfusion Injury-Modulated Proteins in Cardiac Microvascular Endothelial Cells and the Protective Role of Tongxinluo

Author(s) -

Qing Li,

Hehe Cui,

Yue-jin Yang,

Xiangdong Li,

Gui-Hao Chen,

Xiaqiu Tian,

Chen Jin,

QiuTing Dong,

Peisen Huang,

Jun Xu

Publication year - 2017

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000470806

Subject(s) - reperfusion injury , microbiology and biotechnology , biology , growth factor , chemistry , biochemistry , ischemia , medicine , receptor

The protection of endothelial cells (ECs) against reperfusion injury has received little attention. In this study, we used Tandem Mass Tag (TMT) labeling proteomics to investigate the modulated proteins in an in vitro model of cardiac microvascular endothelial cells (CMECs) subjected to ischemia/reperfusion (I/R) injury and their alteration by traditional Chinese medicine Tongxinluo (TXL).

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