Factor XIII Deficiency and Thrombocytopenia Are Frequent Modulators of Postoperative Clot Firmness in a Surgical Intensive Care Unit | Zendy

Sarah von Rappard | Zendy; Corina Hinnen | Zendy; Roger Lussmann | Zendy; Manuela Rechsteiner | Zendy; Wolfgang Korte | Zendy

Open Access

Factor XIII Deficiency and Thrombocytopenia Are Frequent Modulators of Postoperative Clot Firmness in a Surgical Intensive Care Unit

Author(s) -

Sarah von Rappard,

Corina Hinnen,

Roger Lussmann,

Manuela Rechsteiner,

Wolfgang Korte

Publication year - 2017

Publication title -

transfusion medicine and hemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.971

H-Index - 39

eISSN - 1660-3818

pISSN - 1660-3796

DOI - 10.1159/000468946

Subject(s) - medicine , clot formation , platelet , fibrinogen , intensive care unit , thromboelastometry , platelet activation , anesthesia , surgery

Fibrinogen and factor XIII (FXIII) have been shown to critically influence clot firmness in the intraoperative setting and thus likely influence intraoperative bleeding. We were interested to identify potential modulators of postoperative clot firmness in a tertiary care hospital surgical intensive care unit setting, independent of their clinical course during surgery.

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