Open AccessEffects of Glycyrrhizin in a Mouse Model of Lung Adenocarcinoma
Author(s) -
Qing-Ping Deng,
Maojie Wang,
Xing Zeng,
George G. Chen,
Run-Yue Huang
Publication year - 2017
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000467897
Subject(s) - glycyrrhizin , pharmacology , cisplatin , lung cancer , toxicity , thromboxane a2 , biology , chemistry , medicine , biochemistry , receptor , chemotherapy
Currently, there is a global attempt to identify potential anti-cancer agents with low toxicity. Previous studies have found that glycyrrhizin exerts anti-cancer action with low toxicity through suppressing thromboxane A2 (TxA2) in lung cancer cell lines. However, these effects have not yet been determined in animal models of lung cancer.
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