Open AccessCytotoxic Effects of Transthyretin Aggregates in an Epidermoid Cell Line
Author(s) -
Vai Hong Fong,
Amandio Vieira
Publication year - 2017
Publication title -
pathobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.941
H-Index - 53
eISSN - 1423-0291
pISSN - 1015-2008
DOI - 10.1159/000466701
Subject(s) - cytotoxic t cell , transthyretin , cell culture , cell , chemistry , biology , microbiology and biotechnology , medicine , pathology , genetics , in vitro
Skin amyloid deposits can occur as part of systemic amyloidoses including those involving misfolded- aggregated transthyretins (agTTR). Pathological effects of agTTR on the skin are not well understood. The main objective of the current study was to examine the toxicity of agTTR upon a human keratinocyte cell line.
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