Pigment Epithelium-Derived Factor Declines in Response to an Oral Glucose Load and Is Correlated with Vitamin D and BMI but Not Diabetes Status in Children and Young Adults
Author(s) -
Allison C. Sylvetsky,
Najy Issa,
Avinash Chandran,
Rebecca J. Brown,
Hussam Alamri,
Gabriella Aitcheson,
Mary Walter,
Kristina I. Rother
Publication year - 2017
Publication title -
hormone research in paediatrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.816
H-Index - 89
eISSN - 1663-2826
pISSN - 1663-2818
DOI - 10.1159/000466692
Subject(s) - pedf , medicine , endocrinology , diabetes mellitus , obesity , type 2 diabetes , vitamin , type 1 diabetes , vitamin d and neurology , vegf receptors
Pigment epithelium-derived factor (PEDF) is associated with obesity and diabetes complications in adults, yet little is known about PEDF in younger individuals. We investigated the relationship between PEDF and various metabolic biomarkers in young healthy volunteers (HV) and similar-aged patients with diabetes (type 1 and type 2).
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