Immune Complex Membranoproliferative Glomerulonephritis Associated with Transjugular Intrahepatic Portosystemic Shunts in Alcoholic Cirrhosis: Two Case Reports | Zendy

Hernández-Jaras Julio | Zendy; Espí-Reig Jordi | Zendy; Alis Rafael | Zendy; García-Martínez Ana-Maria | Zendy; Rodríguez-Ortega Diego | Zendy; Roca-Argente Lourdes | Zendy; Moll-Guillen Jose-Luis | Zendy

Open Access

Immune Complex Membranoproliferative Glomerulonephritis Associated with Transjugular Intrahepatic Portosystemic Shunts in Alcoholic Cirrhosis: Two Case Reports

Author(s) -

Hernández-Jaras Julio,

Espí-Reig Jordi,

Alis Rafael,

García-Martínez Ana-Maria,

Rodríguez-Ortega Diego,

Roca-Argente Lourdes,

Moll-Guillen Jose-Luis

Publication year - 2017

Publication title -

medical principles and practice

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.426

H-Index - 45

eISSN - 1423-0151

pISSN - 1011-7571

DOI - 10.1159/000464365

Subject(s) - case report

Objective: To report on 2 patients with alcoholic cirrhosis who were treated with transjugular intrahepatic portosystemic shunt (TIPS) placement. Clinical Presentation and Intervention: The 2 patients had a history of alcoholic cirrhosis, and TIPS surgery was performed on them. In both cases, 4 months after TIPS placement, proteinuria was observed along with histological alterations characteristic of immune complex membranoproliferative glomerulonephritis (MPGN). Conclusion: The TIPS in one patient was successful without immediate complications, while the other patient was referred for a combined liver-kidney transplant. In both cases, immune complex MPGN might have developed after TIPS placement probably due to a reduced immune complex clearance.

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