Expression of the ERBB Family of Ligands and Receptors in Gastric Cancer
Author(s) -
Sunju Byeon,
Hye Seung Lee,
Mina Kim,
Byung Lan Lee,
Woo Ho Kim
Publication year - 2017
Publication title -
pathobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.941
H-Index - 53
eISSN - 1423-0291
pISSN - 1015-2008
DOI - 10.1159/000464250
Subject(s) - amphiregulin , epiregulin , erbb3 , erbb , epidermal growth factor , tgf alpha , epidermal growth factor receptor , cancer research , biology , receptor , medicine , genetics
Gastric cancer (GC) is the second most common cancer and the third leading cause of cancer-related death in Korea. Alterations in the ERBB (homology to the erythroblastoma viral gene product, v-erbB) receptor family and ERBB-related signaling pathways are frequently observed in GC. However, the roles of the ERBB receptors and their ligands in GC are not well established.
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