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Role of Protease-Activated Receptor 2 in Regulating Focal Segmental Glomerulosclerosis
Author(s) -
Yongjun Wang,
Yanfa He,
Mingzheng Wang,
Pei Lv,
Jianzhen Liu,
Junxia Wang
Publication year - 2017
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000464121
Subject(s) - nephrin , focal segmental glomerulosclerosis , podocyte , glomerulosclerosis , supar , receptor , signal transduction , endocrinology , medicine , biology , kidney , microbiology and biotechnology , glomerulonephritis , proteinuria , urokinase receptor
Background /Aims: The underlying mechanisms leading to focal segmental glomerulosclerosis (FSGS) are lacking. In this report, we examined the role of protease-activated receptors (PARs) subtype PAR2 and its downstream signals in regulating the pathophysiological process of FSGS.

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