LAPTM4B Predicts Axillary Lymph Node Metastasis in Breast Cancer and Promotes Breast Cancer Cell Aggressiveness in Vitro
Author(s) -
Min Xiao,
Shanshan Yang,
Fanling Meng,
Qin Yu,
Yue Yang,
Jia Shusheng,
XiuMing Cai,
Changli Li,
Yuanxi Huang,
Xiaoming Ning
Publication year - 2017
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000464115
Subject(s) - downregulation and upregulation , vimentin , cancer research , metastasis , breast cancer , immunohistochemistry , cell migration , medicine , cell growth , cancer , pathology , western blot , cell , biology , genetics , gene , biochemistry
Lysosome-associated protein transmembrane-4 beta (LAPTM4B) is associated with the prognosis of several human malignancies. In this study, the role of LAPTM4B in the metastatic potential of breast cancer (BC) and its underlying molecular mechanisms were investigated.
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