Mechanical Loading Improves Tendon-Bone Healing in a Rabbit Anterior Cruciate Ligament Reconstruction Model by Promoting Proliferation and Matrix Formation of Mesenchymal Stem Cells and Tendon Cells
Author(s) -
Fanglong Song,
Dawei Jiang,
Tianchen Wang,
Yi Wang,
Fengmei Chen,
Guoxing Xu,
Yifan Kang,
Yinquan Zhang
Publication year - 2017
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000460005
Subject(s) - osteopontin , bone healing , mesenchymal stem cell , tendon , anterior cruciate ligament , chemistry , extracellular matrix , tenascin c , fibrocartilage , matrix (chemical analysis) , alkaline phosphatase , microbiology and biotechnology , anatomy , pathology , biomedical engineering , medicine , biology , osteoarthritis , biochemistry , articular cartilage , alternative medicine , chromatography , enzyme
This study investigated the effect of mechanical stress on tendon-bone healing in a rabbit anterior cruciate ligament (ACL) reconstruction model as well as cell proliferation and matrix formation in co-culture of bone-marrow mesenchymal stem cells (BMSCs) and tendon cells (TCs).
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