Hyper-Elongation in Colorectal Cancer Tissue – Cerotic Acid is a Potential Novel Serum Metabolic Marker of Colorectal Malignancies | Zendy

Adriana Mika | Zendy; Jarek Kobiela | Zendy; Aleksandra Czumaj | Zendy; Michael S. Chmielewski | Zendy; Piotr Stepnowski | Zendy; Tomasz Śledziński | Zendy

Open Access

Hyper-Elongation in Colorectal Cancer Tissue – Cerotic Acid is a Potential Novel Serum Metabolic Marker of Colorectal Malignancies

Author(s) -

Adriana Mika,

Jarek Kobiela,

Aleksandra Czumaj,

Michael S. Chmielewski,

Piotr Stepnowski,

Tomasz Śledziński

Publication year - 2017

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000458431

Subject(s) - elongation , colorectal cancer , medicine , body mass index , cancer , pathology , chemistry , gastroenterology , endocrinology , materials science , metallurgy , ultimate tensile strength

Colorectal cancer (CRC) cells show some alterations of lipid metabolism. Elongation of fatty acids (FA) has not been studied in CRC tissues thus far. The aim of this study was to verify if CRC specimens and normal colon mucosa differ in terms of their levels of very long-chain FAs, a product of FA elongation. Moreover, the expression of elongase genes has been studied in normal tissue and CRC. Finally, we searched for some specific products of FA elongation in serum of CRC patients.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research