Congenital Cytomegalovirus Infection in the Absence of Maternal Cytomegalovirus-IgM Antibodies
Author(s) -
Julia Gunkel,
Bloeme J. van der Knoop,
Joppe Nijman,
Linda S. de Vries,
G. T. R. Manten,
Peter G. J. Nikkels,
JeanLuc Murk,
Johanna I.P. de Vries,
Tom F.W. Wolfs
Publication year - 2017
Publication title -
fetal diagnosis and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.976
H-Index - 60
eISSN - 1421-9964
pISSN - 1015-3837
DOI - 10.1159/000456615
Subject(s) - serostatus , medicine , cytomegalovirus , serology , fetus , pregnancy , immunology , antibody , herpesviridae , virus , viral disease , biology , viral load , genetics
Congenital cytomegalovirus (cCMV) infections are the most prevalent intrauterine infections worldwide and are the result of maternal primary or non-primary infections. Early maternal primary infections are thought to carry the highest risk of fetal developmental abnormalities as seen by ultrasound; however, non-primary infections may prove equally detrimental.
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