MicroRNA-183 Suppresses Neuropathic Pain and Expression of AMPA Receptors by Targeting mTOR/VEGF Signaling Pathway | Zendy

Xiaojuan Xie | Zendy; Ligang Ma | Zendy; Kai Xi | Zendy; Wei Zhang | Zendy; Dongmei Fan | Zendy

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MicroRNA-183 Suppresses Neuropathic Pain and Expression of AMPA Receptors by Targeting mTOR/VEGF Signaling Pathway

Author(s) -

Xiaojuan Xie,

Ligang Ma,

Kai Xi,

Wei Zhang,

Dongmei Fan

Publication year - 2017

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000455987

Subject(s) - pi3k/akt/mtor pathway , neuropathic pain , receptor , downregulation and upregulation , signal transduction , ampa receptor , medicine , neuroscience , chemistry , pharmacology , microbiology and biotechnology , biology , glutamate receptor , biochemistry , gene

Neuropathic pain is a type of chronic pain that results from dysfunctions of the somatosensory nerve system. This study was aimed to investigate the effect of mTOR/VEGF signaling pathway on neuropathic pain and the regulation mechanisms of miR-183 on AMPA Receptors through mTOR/VEGF signaling pathway.

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