Role for Target of Rapamycin (mTOR) Signal Pathway in Regulating Neuronal Injury after Intracerebral Hemorrhage | Zendy

Jieping Wang | Zendy; Mengyu Zhang | Zendy

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Role for Target of Rapamycin (mTOR) Signal Pathway in Regulating Neuronal Injury after Intracerebral Hemorrhage

Author(s) -

Jieping Wang,

Mengyu Zhang

Publication year - 2017

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000455983

Subject(s) - pi3k/akt/mtor pathway , p70 s6 kinase 1 , ribosomal protein s6 , signal transduction , rptor , phosphorylation , mechanistic target of rapamycin , rheb , microbiology and biotechnology , cancer research , medicine , biology , mtorc1

Mammalian target of rapamycin (mTOR) is a serine/threonine protein kinase and activation of its signal pathway plays an important role in regulating protein growth and synthesis as well as cell proliferation and survival. In the present study, we examined the contribution of mTOR signal and its downstream products to brain injuries induced by intracerebral hemorrhage (ICH) in rats.

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