Camel Whey Protein Protects B and T Cells from Apoptosis by Suppressing Activating Transcription Factor-3 (ATF-3)-Mediated Oxidative Stress and Enhancing Phosphorylation of AKT and IκB-α in Type I Diabetic Mice | Zendy

Gamal Badr | Zendy; Leila H. Sayed | Zendy; Hossam El-Din M. Omar | Zendy; Ali M. Abd El-Rahim | Zendy; Emad A. Ahmed | Zendy; Mohamed H. Mahmoud | Zendy

Open Access

Camel Whey Protein Protects B and T Cells from Apoptosis by Suppressing Activating Transcription Factor-3 (ATF-3)-Mediated Oxidative Stress and Enhancing Phosphorylation of AKT and IκB-α in Type I Diabetic Mice

Author(s) -

Gamal Badr,

Leila H. Sayed,

Hossam El-Din M. Omar,

Ali M. Abd El-Rahim,

Emad A. Ahmed,

Mohamed H. Mahmoud

Publication year - 2017

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000455935

Subject(s) - proinflammatory cytokine , endocrinology , oxidative stress , immune system , medicine , protein kinase b , apoptosis , streptozotocin , spleen , downregulation and upregulation , diabetes mellitus , inflammation , chemistry , immunology , biology , biochemistry , gene

Diabetes mellitus (DM) is associated with severe immune system complications. Camel whey protein (CWP) decreases free radicals (ROS) and modulates immune functions, but its effect on DM-impaired immune systems has not been studied. We investigated the impact of CWP on the immune system in a Type 1 diabetes mouse model.

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