Role of Insulin in Placental Transport of Nutrients in Gestational Diabetes Mellitus | Zendy

María RuízPalacios | Zendy; Antonio J. RuizAlcaraz | Zendy; María Sánchez-Campillo | Zendy; Elvira Larqué | Zendy

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Role of Insulin in Placental Transport of Nutrients in Gestational Diabetes Mellitus

Author(s) -

María RuízPalacios,

Antonio J. RuizAlcaraz,

María Sánchez-Campillo,

Elvira Larqué

Publication year - 2017

Publication title -

annals of nutrition and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.926

H-Index - 81

eISSN - 1421-9697

pISSN - 0250-6807

DOI - 10.1159/000455904

Subject(s) - endocrinology , insulin , medicine , gestational diabetes , fetus , placenta , insulin receptor , diabetes mellitus , pregnancy , biology , insulin resistance , gestation , genetics

Gestational diabetes mellitus (GDM) is associated with increased fetal adiposity, which may increase the risk of obesity in adulthood. The placenta has insulin receptors and maternal insulin can activate its signaling pathways, affecting the transport of nutrients to the fetus. However, the effects of diet or insulin treatment on the placental pathophysiology of GDM are unknown.

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