Open AccessThe IONA® Test: Development of an Automated Cell-Free DNA-Based Screening Test for Fetal Trisomies 13, 18, and 21 That Employs the Ion Proton Semiconductor Sequencing Platform
Author(s) -
Francesco Crea,
Matthew Forman,
Rachel Hulme,
Robert Old,
Dan Ryan,
Rosalyn Mazey,
Michael D. Risley
Publication year - 2017
Publication title -
fetal diagnosis and therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.976
H-Index - 60
eISSN - 1421-9964
pISSN - 1015-3837
DOI - 10.1159/000455025
Subject(s) - cell free fetal dna , false positive rate , medicine , trisomy , workflow , fetus , genetics , biology , prenatal diagnosis , computer science , artificial intelligence , pregnancy , database
To develop a screening test for fetal trisomy 13, 18, and 21 using cell-free DNA from maternal blood with an automated workflow using the Ion Proton sequencing platform.
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