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Prognostic Role of HER2 Status and Adjuvant Trastuzumab Treatment in Lymph Node-Negative Breast Cancer Patients - a Retrospective Single Center Analysis
Author(s) -
Nina Fokter Dovnik,
Andraž Dovnik,
Nina Čas Sikošek,
Maja Ravnik,
Darja Arko,
Iztok Takač
Publication year - 2016
Publication title -
breast care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.767
H-Index - 30
eISSN - 1661-3805
pISSN - 1661-3791
DOI - 10.1159/000454690
Subject(s) - medicine , trastuzumab , oncology , breast cancer , hazard ratio , proportional hazards model , adjuvant , lymph node , retrospective cohort study , confidence interval , adjuvant therapy , cancer
The natural course of traditionally prognostically unfavorable human epidermal growth factor receptor 2 (HER2)-positive breast cancer has been changed by anti-HER2 therapy. It is not clear whether the prognosis for HER2-positive patients treated with adjuvant trastuzumab differs from that of HER2-negative patients.

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