The Role of TLR4 in M1 Macrophage-Induced Epithelial-Mesenchymal Transition of Peritoneal Mesothelial Cells | Zendy

Jun Shi | Zendy; Qing Li | Zendy; Meixiao Sheng | Zendy; Min Zheng | Zendy; Manshu Yu | Zendy; Lu Zhang | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

The Role of TLR4 in M1 Macrophage-Induced Epithelial-Mesenchymal Transition of Peritoneal Mesothelial Cells

Author(s) -

Jun Shi,

Qing Li,

Meixiao Sheng,

Min Zheng,

Manshu Yu,

Lu Zhang

Publication year - 2016

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000453204

Subject(s) - mesothelial cell , epithelial–mesenchymal transition , macrophage , microbiology and biotechnology , mesothelium , mesenchymal stem cell , tlr4 , peritoneum , chemistry , transition (genetics) , cancer research , biology , signal transduction , medicine , pathology , in vitro , biochemistry , gene

Peritoneal fibrosis is a frequent complication of peritoneal dialysis that follows inflammation. It is recognized that epithelial-mesenchymal transition (EMT) of peritoneal mesothelial cells (PMCs), plays a key role in fibrogenesis. However, the relationship between inflammatory macrophages and PMCs remains elusive. In this study, we investigated the effects of different polarized macrophages on EMT of HMrSV5 PMCs.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research