Endothelin Receptor Down-Regulation Mediated Ligand Regulation Mechanisms Protect Against Cellular Hypoxia Injury in Rat Vascular Endothelial Cells
Author(s) -
Long Li,
Mushuang Hu,
Long Zheng,
Chao Zhang,
Jiawei Li,
Ruiming Rong,
Tongyu Zhu,
Yichen Jia
Publication year - 2016
Publication title -
cellular physiology and biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.486
H-Index - 87
eISSN - 1421-9778
pISSN - 1015-8987
DOI - 10.1159/000453196
Subject(s) - small interfering rna , hypoxia (environmental) , enos , endothelin 1 , endothelial stem cell , receptor , microbiology and biotechnology , transfection , gene silencing , messenger rna , cell culture , apoptosis , vascular smooth muscle , downregulation and upregulation , chemistry , in vitro , endocrinology , medicine , biology , nitric oxide synthase , nitric oxide , biochemistry , oxygen , gene , genetics , organic chemistry , smooth muscle
Investigation of the effect of endothelin receptor A (ETaR)-targeting small interfering RNA (siRNA) on rat vascular endothelial cellular hypoxia injury, as well as its underlying mechanism.
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