Improvement of Huangqi Decoction on Endothelial Dysfunction in 5/6 Nephrectomized Rats | Zendy

Shuang Chu | Zendy; Li Wang | Zendy; Xiaodong Mao | Zendy; Wen Peng | Zendy

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Improvement of Huangqi Decoction on Endothelial Dysfunction in 5/6 Nephrectomized Rats

Author(s) -

Shuang Chu,

Li Wang,

Xiaodong Mao,

Wen Peng

Publication year - 2016

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000453188

Subject(s) - endothelial dysfunction , oxidative stress , endocrinology , medicine , endothelium , kidney , pharmacology , chemistry

Endothelial dysfunction is a major factor in the progression of chronic kidney disease, which correlates with oxidative stress and NO deficiency. Huangqi decoction (HQD) is a potential anti-oxidant ingredient in renoprotection. However, the underlying mechanisms remained identified. Therefore, we investigated whether HQD exhibit improvement in endothelial dysfunction in the 5/6 nephrectomy (Nx) rat model.

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