The mTORC2/Akt/NFκB Pathway-Mediated Activation of TRPC6 Participates in Adriamycin-Induced Podocyte Apoptosis | Zendy

Haitao Zhang | Zendy; Weiwei Wang | Zendy; Lihong Ren | Zendy; Xia-Xia Zhao | Zendy; ZhiHui Wang | Zendy; De-Li Zhuang | Zendy; Yun-Nuo Bai | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

The mTORC2/Akt/NFκB Pathway-Mediated Activation of TRPC6 Participates in Adriamycin-Induced Podocyte Apoptosis

Author(s) -

Haitao Zhang,

Weiwei Wang,

Lihong Ren,

Xia-Xia Zhao,

ZhiHui Wang,

De-Li Zhuang,

Yun-Nuo Bai

Publication year - 2016

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000453163

Subject(s) - trpc6 , gene knockdown , protein kinase b , apoptosis , pi3k/akt/mtor pathway , podocyte , cancer research , mtorc1 , mg132 , chemistry , propidium iodide , microbiology and biotechnology , biology , endocrinology , receptor , programmed cell death , kidney , biochemistry , proteasome inhibitor , transient receptor potential channel , proteinuria

Although increased expression and gain function of transient receptor potential cation channel 6 (TRPC6) has been associated with the pathogenesis of some proteinuric glomerular diseases, it remains elusive how TRPC6 participates in the process of podocyte damage.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research