The Vigabatrin Induced Retinal Toxicity is Associated with Photopic Exposure and Taurine Deficiency: An In Vivo Study | Zendy

Ye Tao | Zendy; Jixue Yang | Zendy; Zhao Ma | Zendy; Zhongjun Yan | Zendy; Ce Liu | Zendy; Jianjie Ma | Zendy; Yunqin Wang | Zendy; Zhen Yang | Zendy; Yi Huang | Zendy

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The Vigabatrin Induced Retinal Toxicity is Associated with Photopic Exposure and Taurine Deficiency: An In Vivo Study

Author(s) -

Ye Tao,

Jixue Yang,

Zhao Ma,

Zhongjun Yan,

Ce Liu,

Jianjie Ma,

Yunqin Wang,

Zhen Yang,

Yi Huang

Publication year - 2016

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000453143

Subject(s) - vigabatrin , retinal , photopic vision , toxicity , electroretinography , erg , taurine , retina , in vivo , biology , pharmacology , endocrinology , medicine , ophthalmology , neuroscience , biochemistry , epilepsy , anticonvulsant , amino acid , microbiology and biotechnology

Retinal toxicity is one of the most commonly discussed and concerning adverse effects of vigabatrin (VGB). The present study explored the relationship between the VGB elicited retinal toxicity, photopic exposure, and taurine deficiency, aiming at screening for risk factors to minimize the adverse effects of VGB.

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