Roles of 1,25(OH)2D3 and Vitamin D Receptor in the Pathogenesis of Rheumatoid Arthritis and Systemic Lupus Erythematosus by Regulating the Activation of CD4+ T Cells and the PKCδ/ERK Signaling Pathway | Zendy

Xiaojie He | Zendy; Yan Ding | Zendy; Wei Xiang | Zendy; Xiqiang Dang | Zendy

Open Access

Roles of 1,25(OH)2D3 and Vitamin D Receptor in the Pathogenesis of Rheumatoid Arthritis and Systemic Lupus Erythematosus by Regulating the Activation of CD4+ T Cells and the PKCδ/ERK Signaling Pathway

Author(s) -

Xiaojie He,

Yan Ding,

Wei Xiang,

Xiqiang Dang

Publication year - 2016

Publication title -

cellular physiology and biochemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.486

H-Index - 87

eISSN - 1421-9778

pISSN - 1015-8987

DOI - 10.1159/000453135

Subject(s) - calcitriol receptor , txnip , pathogenesis , endocrinology , medicine , immunology , rar related orphan receptor gamma , vitamin d and neurology , peripheral blood mononuclear cell , biology , foxp3 , immune system , in vitro , oxidative stress , biochemistry , thioredoxin

The study aims to elucidate the roles of 1,25(OH)2D3 and vitamin D receptor (VDR) in the pathogenesis of rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) by regulating the activation of CD4+ T cells and the PKCδ/ERK signaling pathway.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research