Use of Statins and Risk of Reducing Glaucoma: Is There a Link

glaucoma as those who did not use statin; they also found (importantly) that a higher statin dosage results in a higher risk of developing glaucoma. Since the recent evidence regarding whether or not statin use has a protective effect against glaucoma is controversial, it is necessary to explore the potential reasons. Firstly, the conflict could be due to the study design and methodology used. Recall bias might be present in the case-control studies, and information bias or lost to follow-up generally exists in the cohort studies. There are several differences between these studies, such as the kind and dosage of statins exposure and primary outcomes. Furthermore, the adjusted confounding factors might have influenced the outcomes, such as the frequency of eye care visits. In summary, certain suggestions should be considered regarding the possible protective effect of statin on glaucoma development. Treatment should be studied in randomized controlled trials to collect higher-quality longitudinal data. Statins should be explored as a new strategy for the treatment of glaucoma, especially for those patients whose IOP was lowered but there was visual loss. During statin use, clinicians should also pay attention to the changes in the visual fields.